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Downloads and Upgrades: GenBank 195, Cytoscape 3.0.1, and more


GenBank Release 195.0 is now available via ftp from the National Center for Biotechnology Information.

Uncompressed flatfiles for 195.0 require roughly 594 GB for sequence files only. The ASN.1 data require approximately 490 GB.

Cytoscape 3.0.1 is available here.

The release addresses over 100 bugs and issues noted in previous versions among other updates.

The Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco has released chemViz 1.2, a cheminformatics plug in for Cytoscape 2.8.3.

The release includes tools to calculate the maximum common substructure of a group of nodes, a rewritten 2D structure renderer, and several new chemical descriptor calculations among other updates.

Release 18 of Ensembl Genomes is available here.

This release includes several new species for all divisions of Ensembl Genomes includes three new genomes in Ensembl Fungi; one new genome in Ensembl Protists; four new genomes in Ensembl Metazoa; one new species in Ensembl Plants among other updates.

Filed under

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.