Skip to main content
Premium Trial:

Request an Annual Quote

Downloads and Upgrades: FastROCS 1.4, ImmPort, and RefSeq 59


OpenEye has released FastROCS 1.4, the latest version of its application for virtual screening, lead hopping, and shape clustering.

This release fixes several bugs and eliminates the need for a separate installation of the OpenEye toolkits, which should make client applications more portable and easier to write. In addition, a new example web page service, FlaskROCS, has been added as a starting point for end-user customization.

The National Institute of Allergy and Infectious Diseases is making data on transplantation, vasculitis, and vaccination publically available through the Immunology and Data Analysis Portal, or ImmPort — a repository for NIAID-funded experimental research into the human immune system (BI 2/8/2013).

The release includes de-identified clinical and molecular data from over 1400 study subjects from 11 studies and trials. Four studies are from the Cooperative Clinical Trials in Pediatric Transplantation, a study of nearly 500 children and young adults who received a transplanted kidney between 2001 and 2007. Initial data is also being released from the RAVE study from the Immune Tolerance Network, exploring the use of Rituximab for the treatment of Wegener’s granulamatosis and microscopic polyangiitis.

RefSeq 59 is now available from the National Center for Biotechnology Informatics via FTP.

This release incorporates genomic, transcript, and protein data available as of April 29, and includes 39,040,745 records, 31,593,499 proteins, 3,579,371 RNAs, and sequences from 24,656 different organisms.

The Scan

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.

Neurological Outcomes Linked to Innate Immune Features After Cardiac Arrest

Researchers reporting in Med dig into immune features found a few hours after cardiac arrest that correspond with neurological outcomes.

Mouse Study Finds Circadian Rhythm-Related Gene Expression Changes Linked to Sleep Apnea

A paper in PLOS Biology reveals tissue-specific circadian rhythm and gene expression patterns in an intermittent hypoxia-based mouse model of obstructive sleep apnea.

Polygenic Risk Score to Predict Preeclampsia, Gestational Hypertension in Pregnant Women

Researchers in Nature Medicine provide new mechanistic insights into the development of hypertensive disorders of pregnancy, which may help develop therapeutics.