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Downloads and Upgrades: Ensembl REST API, Reactome 42, Bio-Formats 4.4.4, OMERO 4.4.4

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The European Bioinformatics Institute has released a beta version of its programming-language-agnostic REST API for data from Ensembl 68.

The initial release, available here, provides access to sequences, the Variant Effect Predictor, homologies, gene trees, and assembly and coordinate mapping.


Reactome 42 is available here.

Topics with new or revised information include immune system, disease, cell cycle, metabolism, membrane trafficking, and gene expression. New pathway illustrations include signal transduction, signaling by hippo, signaling by SCF-KIT, and mitochondrial protein import.


The OME Consortium has released Bio-Formats 4.4.4 and OMERO 4.4.4.

The latest version of Bio-Formats includes bug fixes, support for Zeiss AxioVision TIFF datasets and Leica SCN datasets, and API support for large image "pyramids."

OMERO 4.4.4 is primarily a bug-fix release.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.