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Downloads and Upgrades: Ensembl REST API, Reactome 42, Bio-Formats 4.4.4, OMERO 4.4.4

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The European Bioinformatics Institute has released a beta version of its programming-language-agnostic REST API for data from Ensembl 68.

The initial release, available here, provides access to sequences, the Variant Effect Predictor, homologies, gene trees, and assembly and coordinate mapping.


Reactome 42 is available here.

Topics with new or revised information include immune system, disease, cell cycle, metabolism, membrane trafficking, and gene expression. New pathway illustrations include signal transduction, signaling by hippo, signaling by SCF-KIT, and mitochondrial protein import.


The OME Consortium has released Bio-Formats 4.4.4 and OMERO 4.4.4.

The latest version of Bio-Formats includes bug fixes, support for Zeiss AxioVision TIFF datasets and Leica SCN datasets, and API support for large image "pyramids."

OMERO 4.4.4 is primarily a bug-fix release.

The Scan

Boosters Chasing Variants

The New York Times reports that an FDA advisory panel is to weigh updated booster vaccines for COVID-19.

Not Yet

The World Health Organization says monkeypox is not yet a global emergency, the Washington Post reports.

More Proposed for Federal Research

Science reports that US House of Representatives panels are seeking to increase federal research funding.

PLOS Papers on Breast Cancer Metastasis, Left-Sided Cardiac Defects, SARS-CoV-2 Monitoring

In PLOS this week: link between breast cancer metastasis and CLIC4, sequencing analysis of left-sided cardiac defects, and more.