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Downloads and Upgrades: Ensembl Genomes 19, Galaxy CloudMan, and more


Release 19 of Ensembl Genomes is available here.

The release includes new and updated genomes and associated data in Ensembl bacteria, Ensembl metazoa, Ensembl fungi, Ensembl plants, and Ensembl protists.

The Galaxy development team has released an updated version of Galaxy CloudMan — a cloud-enabled version of the web-based platform for biomedical research.

Updates include the unification of Galaxy tools and data file systems into a single file system; support for Hadoop-type workloads and cluster federation via HTCondor; and a service for the Galaxy Reports webapp among other features.

CLC Bio and SciEngines have launched a beta version of a combined solution comprised of CLC Bio's sequence analysis software and the newest model of SciEngines' field programmable gate array-based platform-based Rivyera computers.

The combined solution is the result of a partnership between the two companies that began last year (BI 1/132012).

Version 5.1 of OpenMM, a software library and application for molecular dynamics simulations on high-performance computer architecture, is available here.

This release includes Gromacs TOP files and support for Intel’s OpenCL among other features.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.