Skip to main content
Premium Trial:

Request an Annual Quote

Downloads and Upgrades: Certara's Phoenix; TopHat 2.0.0; CLC Bio


Certara has released a new version of Phoenix, its pharmacokinetic/pharmacodynamic modeling software platform.

Version 1.3 includes updates to several Certara products including Phoenix WinNonlin 6.3; Phoenix NLME 1.2; Phoenix Connect 1.3; AutoPilot Toolkit 2.1 for Phoenix; and IVIVC Toolkit 2.1 for Phoenix WinNonlin

These updates include an improved sampling method for the Quasi-Random Parametric Expectation Maximization algorithm in Phoenix NLME; increased support for developing integrated workflows that include algorithms from third-party software in Phoenix Connect; the ability to execute third-party compute jobs on a high-performance compute cluster through a remote processing server; and other changes.

The Center for Bioinformatics and Computational Biology at the University of Maryland has released TopHat 2.0.0.

The release supports Bowtie 2 and provides improved parallelization and the ability to align RNA sequencing reads across potential fusion points, among other updates.

CLC Bio no longer offers three desktop software packages: CLC DNA Workbench, CLC RNA Workbench, and CLC Protein Workbench.

The features from these three products have been incorporated into the CLC Main Workbench for sequence analysis and gene expression analysis.

The company has also lowered the price of the CLC Main Workbench from $3,950 to $1,999 for industrial customers and from $985 to $399 for academic customers for static single computer licenses. Network licenses now cost $3,999 and $799 for industry and academia, respectively.

The company has also added a limited-term $179 price reduction for the workbench for academic researchers that will last until May 31.

The Scan

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.

Study Reveals Potential Sex-Specific Role for Noncoding RNA in Depression

A long, noncoding RNA called FEDORA appears to be a sex-specific regulator of major depressive disorder, affecting more women, researchers report in Science Advances.

New mRNA Vaccines Offer Hope for Fighting Malaria

A George Washington University-led team has developed mRNA vaccines for malaria that appear to provide protection in mice, as they report in NPJ Vaccines.

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.