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Downloads and Upgrades: CCDS 14, dbSNP 139, and Accelrys BioRails 4.5 and Morphit 3.0

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The National Center for Biotechnology Information has updated the Consensus Coding Sequence for Homo sapiens annotation release 105. The release includes a total of 28,694 CCDS IDs that correspond to 18,673 GeneIDs. This update also adds 978 new CCDS IDs and 74 Genes into the human CCDS set.

The new data is available on the CCDS website and via ftp.

The NCBI has also released dbSNP Build 139 for several organisms, including gorilla, horse, dog, sheep, rabbit, opossum, platypus, wild turkey, zebra finch, tomato, grape, and aspergillus.


Accelrys has released an updated version of its biology assay and study management software suite which consists of Accelrys BioRails DM 4.5, Accelrys BioRails PTO 4.5, and Accelrys Morphit 3.0.

The suite offers a comprehensive solution for capturing, processing, analyzing, and reporting low to medium-throughput in vitro and in vivo biological data and associated workflows. In this release, BioRails is integrated with the Accelrys Enterprise Platform and Scientific Component Collections and includes color-coded workflows that enable project managers track the status of work in progress and prioritize jobs across teams and individuals among other changes.

Morphit 3.0 offers out-of-the-box pharmacokinetics tools that use industry-standard formulas for calculating area under curve, clearance, half life and other PK parameters, enhanced charting capabilities, and tighter integration with Microsoft Excel spreadsheets among other updates.


The Scan

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.

DNA Biobank Developed for French Kidney Donors, Recipients

The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France.

Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut

By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site.

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.