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Downloads and Upgrades: Archer Analysis Pipeline, POSIT 3.1, and Lasergene 12.1


Enzymatics has launched version 3.0 of its Archer Analysis Pipeline. It's the latest incarnation of the company's next-generation sequence analysis platform for detecting and characterizing cancer-causing gene fusions and mutations from clinical samples. The solution lets users call known or novel genomic alterations. It includes robust quality control systems, clear, detailed analytics, and interactive visualizations using JBrowse, among other features.

OpenEye has released POSIT 3.1, a new version of a component in its OEDocking suite that's used for pose prediction in lead optimization experiments. Enhancements to POSIT include the addition of HybridFit and SiteFit search technology as well as support for an unlimited number of receptors, and MPI-enabled parallel processing.

DNAStar has released Lasergene 12.1. This version of the solution integrates the company's traditional desktop software with cloud capabilities providing users with tools to run multiple sequence assemblies on remote infrastructure. The solution also includes DNAStar data drive, which enables fast, secure data transfer between desktop computers and the cloud. It also includes protein function and binding site prediction tools and more.

The Scan

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.

Neurological Outcomes Linked to Innate Immune Features After Cardiac Arrest

Researchers reporting in Med dig into immune features found a few hours after cardiac arrest that correspond with neurological outcomes.

Mouse Study Finds Circadian Rhythm-Related Gene Expression Changes Linked to Sleep Apnea

A paper in PLOS Biology reveals tissue-specific circadian rhythm and gene expression patterns in an intermittent hypoxia-based mouse model of obstructive sleep apnea.

Polygenic Risk Score to Predict Preeclampsia, Gestational Hypertension in Pregnant Women

Researchers in Nature Medicine provide new mechanistic insights into the development of hypertensive disorders of pregnancy, which may help develop therapeutics.