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Downloads and Upgrades: AFITT 2.2.0, OncoGenomics Explorer, Omics Explorer 2.3, and more


OpenEye has released AFITT 2.2.0, an application designed to help crystallographers fit ligands to observed data.

The release has several bug fixes including support for current versions of the REFMAC, additional ligand scores for all ligands, and corrections to aniline nitrogen dictionaries.

OpenEye also released VIDA 4.2.1.

The release includes several bug fixes as well as a new telemodeling feature, improved 3D graphics, and updates to VIDA’s spreadsheet function among other capabilities.

Finally, OpenEye released VIVANT 4.2.0, the latest version of its molecular modeling software

The release fixes several bugs, improves rendering using hardware shaders, and caches state files loaded from remote websites.

MediSapiens has launched OncoGenomics Explorer, a cloud computing-based application for drug discovery and repositioning.

The application provides tools for users to mine, visualize, and analyze different kinds of genomics data. It also lets researchers stratify and recruit patients for clinical trials based on their genetic profiles.

BioFortis has launched its Next Generation Biobanking software, which is intended for use in biomarker-based clinical research in pharmaceutical, government, and academic research centers.

The application incorporates BioFortis’s Labmatrix platform, which provides tools to integrate patient, clinical, specimen, genetic, and molecular assay data. It also offers multi-level user access control, which enables collaboration while maintaining relevant privacy and regulatory compliance objectives; as well as the Qiagram tool, which lets users create queries and presents answers in configurable visualizations and dashboard widgets that can be shared.

Qlucore has released Qlucore Omics Explorer 2.3.

The release includes new features such as box plots, line plots, and histogram plots, which help researchers visualize, explore, and analyze high-dimensional data sets interactively and in real time.

This week, Panasas released ActiveStor 14, the latest version of its parallel storage solution.

ActiveStor 14 leverages enterprise SATA drives to provide more than eight petabytes of scalable storage. It also incorporates SSD technology to accelerate small file performance and metadata operations while minimizing SSD wear and expense.

DNAStar has released Lasergene 10.1, the latest version of its sequence assembly and analysis software, which now includes automated bacterial genome closure and epitope prediction capabilities.

Furthermore, version 10.1 includes phenotypic data in clinical trial genomic data analysis and provides additional statistics.

RefSeq 55 is now available from the National Center for Biotechnology Information via FTP.

The release incorporates genomic, transcript, and protein data available as of Sept. 17, and includes 23,207,572 records, 17,368,769 proteins, 3,137,878 RNAs, and sequences from 17,994 different organisms.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.