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Downloads and Upgrades: May 6, 2011


This week, LabArchives released a new version of its Electronic Laboratory Notebook.

The tool lets users store and retrieve different types of documents including images, view earlier versions of pages or documents with details of changes that were made, create and use templates for routine laboratory tasks, and tag entries using a user-defined controlled vocabulary, among other features.

Current customers will receive the upgrade free of charge.

The Center for Bioinformatics and Computational Biology at the University of Maryland has released Cufflinks version 1.0.1

The new version includes a reference annotation based transcript assembly mode, improvements to Cuffdiff, bias correction, added support for handling multi-mapping reads, and several bug fixes, among other updates.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.