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Downloads and Upgrades: Apr 1, 2011

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Version 52 of the Catalogue of Somatic Mutations in Cancer, COSMIC, is now available.

In addition to website improvements, the new release includes four new genes and 16 new fusion pairs curated from the literature as well as updates to the Cancer Genome Atlas and the International Cancer Genome Consortium portal data.


This week, Accelrys launched Accelrys Modeling and Simulation Suite.

The tool suite incorporates the firm’s Discovery Studio software, Materials Studio software, the Pipeline Pilot Life Science and Materials Modeling and Simulation Collections, as well as its QSAR Workbench, a packaged solution from Accelrys Professional Services.

The suite offers scientific organizations involved in pharmaceutical, chemical, and materials research; and development access to predictive science capabilities ranging across small molecules, biomolecules, chemicals and materials.

Separately, the company announced the release of Accelrys QSAR Workbench, a web-based solution for developing, validating and deploying of predictive quantitative structure-activity relationship models. The tool captures best practices of QSAR design, streamlines model development, reduces errors, and automates manual steps.


Version 1.9.2 of the open source software UGENE has been released.

The latest version includes bug fixes as well as workflow and query designer improvements among other features. Furthermore, the UGENE Genome Aligner can now use modern GPUs to boost computations.


Velvet 1.1.02 is available here.

This version is multithreaded and can use multiple CPUs on the same computer, has a reduced memory footprint, and improves the use of mate-pairs, and includes corrections to the MetaVelvet Makefile among other updates


The National Center for Biotechnology Information has released BLAST 2.2.25.

The new release fixes several bugs and includes improvements such as enhanced documentation, added support for hard-masking of Blast databases, and added support for query and subject length to tabular output, among other features.


The Scan

Call to Look Again

More than a dozen researchers penned a letter in Science saying a previous investigation into the origin of SARS-CoV-2 did not give theories equal consideration.

Not Always Trusted

In a new poll, slightly more than half of US adults have a great deal or quite a lot of trust in the Centers for Disease Control and Prevention, the Hill reports.

Identified Decades Later

A genetic genealogy approach has identified "Christy Crystal Creek," the New York Times reports.

Science Papers Report on Splicing Enhancer, Point of Care Test for Sexual Transmitted Disease

In Science this week: a novel RNA structural element that acts as a splicing enhancer, and more.