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Downloads and Upgrades: Aug 13, 2010

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SeqCentral announced this week the beta release of its genetic sequence alignment service, which provides access to hundreds and eventually thousands of machines running sequence alignment tools such as the National Center for Biotechnology Information's Blast in a cloud compute infrastructure.

According to the company, the service lets users run searches in parallel, view details of every job they run, store and manage large datasets, and share results with other researchers.

The company plans to release a public version of the service in September but will offer free beta accounts until then.

Users can sign up here.


CLC Bio and PSSC Labs have released CLC Genomics Factory, a full genome analysis platform that includes hardware and software for assembly, read mapping, and downstream analysis of large quantities of high-throughput DNA and RNA sequence data.

Other features include ChIP-sequencing, SNP and DIP detection, small RNA analysis, and Taq profiling.

CLC Genomics Factory comes in three different sizes with varying numbers of compute nodes including a master node and multiple job nodes that can process data from up to 10 Illumina HiSeq2000 or seven Life Technologies SOLiD 4 systems.

The platform comes pre-installed with the CLC Genomics Server and lets CLC Genomics Workbench users interface with the server software through a graphical user interface or a command line interface.

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.