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DNAnexus to Offer BioNano Genomics' IrysSolve Pipeline on Cloud

NEW YORK (GenomeWeb) – DNAnexus and BioNano Genomics have signed an agreement to provide access to IrysSolve, BioNano's whole-genome analysis algorithms and pipeline, on DNAnexus' cloud platform.

IrysSolve is part of BioNano's Irys system, which uses so-called NanoChannel arrays integrated within the IrysChip to image genomes at the single-molecule level. Under the terms of the agreement, DNAnexus will offer a pre-configured version of the BioNano genomics computational pipeline, including applications for assembly, hybrid scaffolding, and structural variation calling, the companies said. Customers will be able to run IrysSolve on their datasets from anywhere in the world as well as securely share data in a centralized environment.

"We are very excited to join technologies with DNAnexus, to provide researchers with fast and cost-effective access to the whole-genome analysis computational power they need to reach their discoveries," BioNano President and CEO Erik Holmlin said in a statement. "We believe with these tools, researchers will spend less time waiting for analyses and more time focusing on results."

Being able to run IrysSolve on the cloud eases the computational burden of performing whole-genome mapping using the Irys system, Tina Graves-Lindsay, leader of the Reference Genomes Group at the McDonnell Genome Institute at Washington University, St. Louis, noted in a statement. Her team is using whole-genome mapping data from the Irys system to confirm the accuracy of whole-genome assemblies as well as for annotation and structural variation analysis as part of their efforts to improve the quality of the human reference genome.

Graves-Lindsay will present her team's research at the American Society of Human Genetics annual meeting in Baltimore this week.