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DNA Software Nets $2.5M in SBIR Funds

NEW YORK (GenomeWeb News) – DNA Software has won three grants totaling $2.5 million from the National Institutes of Health to support the development of its software for use in predicting the structure of bacterial ribosomes and modeling the reaction rates of DNA and RNA experiments.

In one of the grants, the company will use the Phase II Small Business Innovation Research funding to support development of its Nucleic Acid CAD software, which predicts the 3D structures of clinically relevant pathogens.

Half of the antibiotics currently on the market target bacterial ribosomes, but the 3D structures of many of these RNA complexes are still unknown, the Ann Arbor, Mich.-based bioinformatics company said in a statement, adding that knowledge about ribosome structure is critical for the development of new antibiotics for drug-resistant bacteria.

In another project, DNA Software is adding information about kinetics and modified nucleotides to its existing Oligonucleotide Modeling Platform software with the aim of using it to develop selective diagnostics.

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.