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Disease Spotlight, MDS Pharma Express, Insight II, Catalyst 3D, ClearSpeed CS301, GastroPlus, dbSNP build 117, Helicobacter pylori

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Incyte has made its first Disease Spotlight data set, which focuses on breast cancer, freely available through its website (www.incyte.com). The Disease Spotlight is a monthly sampling of the company’s Disease View Reports, a component of its Proteome BioKnowledge Library resource. October’s breast cancer spotlight includes 25 protein reports.


MDS Pharma Services has released version 2.0 of its MDS Pharma Express pharmacology data delivery system, which provides clients with access to preclinical pharmacology data in real time.


Accelrys said it plans to release its Insight II and Catalyst 3D modeling and simulation software suites for the Linux operating system. The company will collaborate with IBM to complete the porting and certify the products on IBM IntelliStation workstations running Red Hat Linux. The products are expected to be commercially available by December 2003.


Chipmaker ClearSpeed Technology has launched the ClearSpeed CS301, a multi-threaded array processor that provides more than twice the processing speed of competitive products, according to the company. ClearSpeed said the chip is well-suited for complex mathematically based applications such as computational biology and drug discovery.


Simulations Plus has released version 4.0 of its GastroPlus software, which simulates the oral absorption of drugs in humans and in laboratory animals. The company said the new version offers more physiologically correct modeling than previous versions.


The National Center for Biotechnology Information has released dbSNP build 117 at ftp://ftp.ncbi.nih.gov/snp/.


Hybrigenics has released its Helicobacter pylori protein-interaction data set in PSI MI format at http://pim.hybrigenics.com.

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The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.