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Deltagen, Dharmacon, Rosetta Inpharmatics, Pfizer, Chiron, TCAG, McGill, Spotfire, Daylight, AstraZeneca, KineMatix


Deltagen Puts its IT Tools on the Block

Online auction house AuctioNet last week said that it will be hosting a live webcast auction of Deltagen’s “surplus IT infrastructure” as part of a broader auction of the company’s lab equipment on Oct. 15 and 16.

Deltagen filed for Chapter 11 bankruptcy in June.

The IT infrastructure, which powered the company’s 132,000-square-foot genomics facility in Redwood City, Calif., includes Dell, Cisco, Sun, Compaq, Hewlett-Packard, Extreme Networks hardware, and an EMC storage area network, AuctionNet said.

Deltagen’s DeltaBase database of mammalian genes and their in vivo functions and DeltaOne online system for purchasing individual target mouse models and information are also for sale, AuctioNet said.

Live auction events will be held at the Deltagen Redwood City facility and on eBay’s Business & Industrial Live Online Auctions. More information about the sale can be found online at

Dharmacon Teams with Rosetta Inpharmatics on siRNA Selection Algorithms

Dharmacon said last week that it has entered into a collaboration with Merck subsidiary Rosetta Inpharmatics “to develop a deeper understanding of factors affecting the potency and specificity of the short interfering RNA (siRNA) reagents used for RNA interference-mediated gene silencing.”

Stephen Scaringe, Dharmacon CSO, told BioInform’s sister publication RNAi News that Dharmacon will be working with Rosetta to refine its siRNA selection algorithms. The work is expected to lead to better siRNAs that could be used in lower concentrations, and therefore eliminate one of the causes of off-target effects.

In June, researchers from Rosetta published a paper in Nature Biotechnology that discussed how Dharmacon’s chemically synthesized siRNAs caused off-target silencing effects in two separate experiments.

Dharmacon retains rights to commercialize certain discoveries resulting from the collaboration.

Pfizer, Chiron, TCAG, McGill License Transfac via Cognia

Cognia said last week that research groups at Pfizer and Chiron have licensed the Transfac Professional transcription regulation database. Cognia distributes the database, which is maintained by Biobase of Wolfenb ttel, Germany.

The company said that the Center for Advanced Genomics and the Department of Bioinformatics at McGill University also licensed the Professional version of the database.

Spotfire Partners with Daylight on Cheminformatics

Spotfire said last week that it has entered a partnership with cheminformatics provider Daylight to offer “Advantage Solutions” that integrate the company’s DecisionSite platform with Daylight’s software for accessing chemical structures and property data.

The Advantage Solutions will provide interfaces to Daylight Toolkits and DayCart, Daylight’s chemistry cartridge for Oracle.

AstraZeneca Selects SGI Altix

SGI last week said that AstraZeneca had purchased an Altix 3000 system and Origin 3000 servers and superclusters for simulation studies at its Wilmington, Del., R&D Facility.

“The new 8-cpu Altix system, based on the Linux operating system and the Intel Itanium 2 processor, will support complex chemistry applications that are now becoming available on Linux platforms, and will do so with a shared memory model,” said Jim Damewood, associate director of chemistry, computational chemistry, and informatics at AstraZeneca.

The Origin and Altix systems were installed at the end of June.

KineMatix, Open Text Donate Software to Irish Research Groups

KineMatik, a Cork, Ireland-based enterprise R&D software provider, and Open Text, an Ontario, Canada-based collaborative software provider, said last week that they will donate their software to two Centers for Science, Engineering, and Technology (CSETs) in Ireland: the Royal College of Surgeons’ National Center for Human Proteomics in Dublin, where researchers will study technologies and proteins that can successfully treat diseases of the heart; and the Alimentary Pharmabiotic Center at University College Cork, where scientists are researching treatments for Crohn’s disease.

KineMatik will provide its eNovator enterprise collaborative R&D solution, and Open Text will provide its Livelink software suite, which offers collaborative workspaces, document management, search capabilities, and process automation. KineMatik’s eNovator is fully integrated with Livelink.

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