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The DDT Launching Pad: Informatics Products at Drug Discovery Technology 2004


GeneGo launched MetaCore 2.0, which includes more than 300 functional maps of human biology, parsers for importing data directly from Affymetrix and Agilent microarrays, and data from Silicon Genetics’ GeneSpring, Rosetta’s Resolver, SAGE, proteomics, and metabolomics data. MetaCore 2.0 also has seven new network-building algorithms, and additional visualization tools.

InforSense launched a new version of the BioScience module for its Knowledge Discovery Environment workflow management platform. The new version of the module offers extended visualization and interpretation capabilities, new workflow components, enhanced external data connectivity, and further facilitates the integration of Perl scripts and applications into InforSense workflows, the company said. The module includes FeatureVista, a new sequence and annotation browser, and the XML Integration Framework Studio for incorporating command-line tools.

Ingenuity Systems announced the “Summer ‘04” release of its Ingenuity Pathways Analysis product, along with a new Ingenuity Enterprise Collaboration application for pharmaceutical and biotechnology companies, an Ingenuity Workgroup Collaboration application for government and non-profit institutions, and Ingenuity University — a two-day course that teaches “best practices” and use of pathways analysis in drug discovery and development. The new release of the company’s flagship product offers a number of new features, including a network comparison capability that allows users to compare up to ten networks; global functional analysis for graphically displaying biological processes across multiple datasets; network merging; and simultaneous analysis of gene and protein experiments. The Enterprise and Workgroup collaboration applications are currently in development. The company said it is seeking beta-testers for these applications, which should be released in the fourth quarter of the year.

Ocimum Biosolutions launched its Pharmatracker LIMS. The system is compliant with GxP requirements as stipulated by the US EPA, US FDA, and WHO, as well as the FDA’s 21 CFR Part 11 requirements on electronic records and electronic signatures. Workflow, stability, QC batch management, and trend analysis tools are provided as part of the system.

Optive Research launched EA-Inventor, a de novo molecular design program based on an evolutionary algorithm that allows chemists to “evolve” new compounds by modifying the structures of an initial set of compounds. Optive said that the software can work with whatever fitness function best describes a user’s specific constraints and discovery objectives. EA-Inventor can work with any third-party scoring function, the company said, and ships with several scoring functions developed by Optive Research.

Spotfire released DecisionSite 8. The new version of the company’s software includes a shared repository for analysis guides, files, and posters, and a SmartLists feature that tracks critical elements such as leads, prospects, lots, and batches. The company also launched the Spotfire DecisionSite Analytics Server, which enables DecisionSite 8 to access data from disparate databases and also links statistics engines from Insightful S-Plus and R into the DecisionSite 8 environment. DecisionSite 8 is available with no additional license fee to all DecisionSite customers under maintenance agreements .


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The Scan

Driving Malaria-Carrying Mosquitoes Down

Researchers from the UK and Italy have tested a gene drive for mosquitoes to limit the spread of malaria, NPR reports.

Office Space to Lab Space

The New York Times writes that some empty office spaces are transforming into lab spaces.

Prion Pause to Investigate

Science reports that a moratorium on prion research has been imposed at French public research institutions.

Genome Research Papers on Gut Microbe Antibiotic Response, Single-Cell RNA-Seq Clues to Metabolism, More

In Genome Research this week: gut microbial response to antibiotic treatment, approach to gauge metabolic features from single-cell RNA sequencing, and more.