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DDI Predict, CLC RNA Workbench, ArrayStar, Platform Open Cluster Stack

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This column has been updated to clarify the roles of Platform Computing and its development partners in the fourth item.  
 
Aureus Pharma has released DDI Predict, a software application designed to automatically calculate the risk of drug-drug interactions associated with cytochrome P450s and provide a graphical report. The analysis of potential DDI risk is based on the US Food and Drug Administration’s latest risk classification, according to the company.
 

 
CLC Bio has released CLC RNA Workbench, a software platform for RNA secondary structure prediction based on free energy minimization algorithms.
 
A free trial of CLC RNA Workbench is available here.
 

 
DNAStar said this week that its ArrayStar microarray data-analysis software is now compatible with Affymetrix arrays under the company’s GeneChip-compatible applications program.
           
 

 
Platform Computing announced at the International Supercomputing Conference in Dresden, Germany, this week that it has collaborated with Intel to develop the Intel Cluster Ready Program.
 
Platform said that its Open Cluster Stack, the first commercial software system that creates "certified" Intel Cluster Ready systems, will be provided to the program. The Intel Cluster Ready program was designed to streamline the process of implementing Linux clusters.
 
Speaking to BioInform from the conference, Gary Tyreman, vice president and business manager of high-performance computing at Platform, said that the launch of the program, of which Platform is a part, is the culmination of about two years' worth of work with Intel and Dell.

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The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.