Tokyo-based Daiichi Pharmaceutical, a subsidiary of Daiichi Sankyo, took a risk five years ago when it opted for a still-unproven in silico approach to predict protein-protein interactions from Celestar Lexico-Sciences.

Daiichi decided to use the approach, which Celestar calls PPIP (protein-protein interaction prediction), as an alternative to the yeast two-hybrid system, which is the most commonly used experimental method for identifying protein-protein interactions, but is notoriously problematic with regard to efficacy and predictability.

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The New York Times and ProPublica say that many physicians fail to disclose their financial ties when publishing in medical journals.

The Wall Street Journal reports Human Longevity's valuation has dropped by 80 percent.

Science reports that the US National Cancer Institute is cutting its operating budget by 5 percent.

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.