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Cytoscape 2.6.0, miRBase 11.0, Biojava 1.6, MIRA 2.9.25, Simcyp Pediatric Simulator

Cytoscape 2.6.0 is available here.
The latest version of the open-source network-visualization platform includes several improvements, including a web service client manager; access to Pathway Commons, IntAct, and NCBI Entrez Gene; synonym import from BioMart; a network manager that supports multiple network selection; and improved label positioning.

The Wellcome Trust Sanger Institute has released a new version of the miRBase database of published microRNA sequences and associated annotation.
Version 11.0 of miRBase, available here, contains 6,396 entries representing hairpin precursor miRNAs, expressing 6,211 mature miRNA products, in primates, rodents, birds, fish, worms, flies, plants, and viruses.

Biojava 1.6 is available here.
The new release, based on Java 1.5+, includes an improved phylogenetics package, an updated PDB file parser, and other improvements.

Version 2.9.25 of the MIRA 2.9.25 sequence assembler is available here.
MIRA 2.9.25 now includes mapping assemblies of Illumina Genome Analyzer reads, SNP detection with Illumina GA reads, an improved command-line interface, simplified handling of hybrid assemblies that involve Sanger, 454, and Illumina GA reads, and other new features.

Simcyp has released a new version of the Simcyp Pediatric Simulator, a modeling and simulation platform that models pharmacokinetic behavior in “virtual populations” of children to help drugmakers better predict dosing for pediatric medications.

Simcyp Pediatric 2008 is available as a module for the company’s Simcyp Population-based ADME Simulator.

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The Scan

And For Adolescents

The US Food and Drug Administration has authorized the Pfizer-BioNTech SARS-CoV-2 vaccine for children between the ages of 12 and 15 years old.

Also of Concern to WHO

The Wall Street Journal reports that the World Health Organization has classified the SARS-CoV-2 variant B.1.617 as a "variant of concern."

Test for Them All

The New York Times reports on the development of combined tests for SARS-CoV-2 and other viruses like influenza.

PNAS Papers on Oral Microbiome Evolution, Snake Toxins, Transcription Factor Binding

In PNAS this week: evolution of oral microbiomes among hominids, comparative genomic analysis of snake toxins, and more.