Skip to main content
Premium Trial:

Request an Annual Quote

Compendia Receives $1.3M SBIR Grant for miRNA Data Project

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Compendia Bioscience today said it has been awarded a $1.3 million Small Business Innovation Research Fast Track grant to incorporate miRNA data and analyses into its Oncomine platform.

The Ann Arbor, Mich.-based bioinformatics firm will capture, curate, and analyze novel miRNA data in a standardized fashion and provide the data and analyses in a user-friendly format "that promotes ongoing inquiry," the firm said in a statement.

While miRNA has increasingly been implicated in cancer development, progression, and metastasis, it is impossible for cancer biologists to survey a patient's differential expression of miRNA across all published datasets, or to integrate knowledge about miRNA expression patterns with other biological phenomena, such as gene expression, copy number, and mutation data, Compendia said.

With the SBIR grant, Compendia will make miRNA data accessible through its Oncomine platform, which contains more than 41,000 curated cancer profiles, while an analysis engine and web application enables data mining and visualization of the profiles.

"This effort will require significant technical innovation to capture, organize, and present data that is both biologically and technically complex in a way that is rapidly comprehensible to the cancer biologist," the company said.

The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.