NEW YORK (GenomeWeb) – Genetic variability within a certain metabolic signaling pathway gene may contribute to the abnormal brain development seen among some preterm infants.

About 11 percent of all births are preterm and more than 30 percent of survivors experience neurocognitive issues during their life, such as anxiety, social, and communication problems, and attention difficulties. Imaging studies have linked these adverse outcomes with changes in brain structure, connectivity, and function.

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With the Next Generation Sequencing (NGS), genomes sequencing has been democratized over the last decades with the detection of genomic alterations, thus replacing Sanger sequencing.