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Coded Electronic Life Library, Ensembl, Bio-perl Toolkit

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Free trials of the Coded Electronic Life Library, or CELL, are now available from Incellico of Durham, NC, at www.incellico.com/cellsuite_ entitybrowser2.html.

CELL provides a searchable, ontology-based network that allows cross-referencing of data in EMBL/GenBank, SwissProt, OMIM, Gene Ontologies, and Medline. It also merges over 40 naming systems for biological entities.

CELL’s Entity Browser interface allows users to graphically browse ontological relationships between genes, proteins, organisms, biochemical pathways, disease models, tissue types, and literature.

 

Version 1.2.0 of Ensembl is now available at www.ensembl.org. Based on data from the UCSC August freeze assembly, the new version includes 25,037 confirmed genes with 28,706 transcripts. Of those, 16,308 transcripts are mapped to known cDNAs. Improvements to the website include a revamped home page and more automatic interlinking of pages to encourage users to take advantage of new tools.

A new view, Cytoview, is available for large-scale viewing of clone resources.

 

The 0.7.2 stable release of the Bio-perl Toolkit is now available at ftp://bioperl.org/pub/DIST/bioperl-0.7.2.tar.gz and the first release of Bioperl-db, a set of modules for storing and retrieving sequence data from a relational database, is available at ftp://bioperl.org/pub/ DIST/bioperl-db-0.1.tar.gz.

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The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.