INDIANAPOLIS--Earlier this month, Eli Lilly here announced a deal with Tokyo-based Chugai Pharmaceutical in which the American firm will share proprietary combinatorial chemistry expertise in exchange for up-front fees, milestone payments, and royalties on the first two products that reach the market as a result of the collaboration. Among the techniques and technologies that will be shared are some gained as a result of Lilly's 1994 acquisition of Sphinx Pharmaceuticals, which significantly expanded Lilly's competence in combinatorial chemistry.

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