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CellSpace Knowledge Miner, ROSE, Jackson Laboratory s Mouse Genome Informatics Database, READIT SNP Genotyping System.

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Pittsburgh-based Cellomics has released its CellSpace Knowledge Miner, a system that continuously monitors the Medline database and automatically extracts and stores information about relationships between molecules.

The system performs proprietary statistical correlation analyses about the organisms, cell types, biological processes, and molecules reported on in biomedical research literature and responds with a consensus answer derived from more than one million research publications. New research literature is automatically analyzed every two weeks.

The University of Bielefeld has released version 1.2 of ROSE (Random-model Of Sequence Evolution).

ROSE implements probabilistic models of RNA, DNA, and protein sequence evolution via insertions, deletions, and substitutions. The data are suitable for the evaluation of methods in multiple sequence alignment computation and the prediction of phylogenetic relationships. New features include standard DNA evolution models and FASTA or PHYLIP output formats.

ROSE is available on the Bielefeld Bioinformatics Server at http:// bibiserv.TechFak.Uni-Bielefeld.DE/rose.

Release 2.7 of the Jackson Laboratory’s Mouse Genome Informatics Database is now available at www.informatics.jax.org.

The new release features enhancements to the Allele query form and a new query field for Promoter Notes to search for when and where a transgene is expressed.

There is also a new section for additional references on the Allele Detail page.

Promega of Madison, Wis., is making its READIT SNP Genotyping System available to select laboratories under its controlled sales program.

The system incorporates a software calculator to facilitate automated SNP scoring, error detection, and statistical analysis of the data. The calculator allows users to electronically transfer and analyze data without manual transcription of results.

The software runs on Windows.

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