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CambridgeSoft, Goldman Sachs, University of Florida, Geospiza, Wellcome Trust, European Bioinformatics Institute, Galapagos, Health Discovery Corporation, DCL Medical Laboratories

CambridgeSoft Raises $21M
Life science informatics developer CambridgeSoft said this week that it has completed a $21 million private equity investment by Goldman Sachs.
In connection with the offering, Raheel Zia, a vice president at Goldman Sachs Principal Investment Area, will join CambridgeSoft's board of directors.
In addition, CambridgeSoft said that it has hired Michael Stapleton as vice president of corporate development (see People in the News, this issue).

Florida Center to Use Geospiza’s Finch for Next-Gen Sequencing
The University of Florida has purchased Geospiza’s lab-management software for its genomics sequencing lab, the company said this week.
Under the agreement, the Interdisciplinary Center for Biotechnology Research's Next Generation DNA Sequencing Laboratory will use Geospiza’s FinchLab platform, which is used for managing labs with multiple genetic analysis technologies, including capillary electrophoresis and next-generation sequencing tools from Applied Biosystems and Roche/454.
Bill Farmerie, associate director at ICBR, said that his group has been using Geospiza’s software to manage data from its capillary electrophoresis sequencers for eight years and that the software has “allowed our bioinformatics group to focus foremost on high-level data analysis for our user community rather than divert time and energy to solving routine data management tasks."
Financial terms of the agreement were not released.

Wellcome Trust Provides $9.4M to Publicly Release Galapagos’ Data Via EBI
The UK’s Wellcome Trust, the European Bioinformatics Institute, and Belgian biotech firm Galapagos have signed an agreement that will open up the rights to databases held by Galapagos division BioFocus DPI for use by public research communities.
Under the terms of the agreement, EBI will use a Wellcome Trust grant of £4.7 million ($9.4 million) to support the transfer of a collection of information on drug properties and a set of Galapagos’ drug-like small molecules to the institute. EBI will incorporate the data into its collection of open-access resources for use in biomedical research.
Galapagos will receive £1.4 million for the data, which it previously offered for license through its BioFocus DPI service division.
The Galapagos databases covered under the agreement are DrugStore, StARLITe, Strudle, Kinase SARfari, and GPCR SARfari.
The agreement does not include the StarDrop software platform, which BioFocus DPI will continue to offer.
"The scientific community worldwide will greatly benefit from the access to these data for aiding predictive drug discovery," Galapagos CEO Onno van de Stolpe said in a statement.

Health Discovery, DCL Ink Cancer Dx Collaboration
Health Discovery Corporation said this week that it has partnered with DCL Medical Laboratories to develop and commercialize diagnostic tests for ovarian, cervical, and endometrial cancers based on support vector machine technology.
Under the agreement, HDC will own the developed intellectual property and DCL will have a sole-use license for applications and new mathematical tools that are developed over the course of the collaboration.
HDC is focused on SVM-based molecular diagnostic tests in genomics, proteomics, digital image analysis, and radiology.
Financial terms of the agreement were not released.

Filed under

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.