Skip to main content
Premium Trial:

Request an Annual Quote

Broad Institute Taps Convey's Hybrid-Core System for Genomic Research


Convey Computer said this week that the Broad Institute has purchased one of its hybrid core computing systems, which will be used to speed up portions of its next-generation sequencing data analysis pipeline.

Specifically, the Broad will use an accelerated version of the Burrows-Wheeler aligner that is implemented on Convey's HC-2 system.

Convey developed and implemented a version of BWA on its platform two years ago that it claimed increased genome reference mapping rates by a factor of 15 compared to commodity servers (BI 10/14/2011).

"With the Convey system, we expect to increase performance of BWA tenfold," Tim Fennell, the informatics director for the Broad's Genomics Platform, said in statement.

Convey’s hybrid-core architecture pairs classic Intel x86 microprocessors with a coprocessor comprised of field-programmable gate arrays.

Customers of the company's platform include the UK's Genome Analysis Center (BI 2/1/2013) and the Jackson Laboratory (BI 4/27/2012). Convey also partners with CLC Bio to provide a combined software and hardware solution for NGS data analysis (BI 4/20/2012).

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.