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Brian Ritchie, John Newton

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Brian Ritchie, formerly CEO and president of Blackstone Computing (most recently Argentys; see p. 1), has joined storage consulting services firm GlassHouse Technologies as senior VP of sales.

 

The UK Biobank has tapped Oxford University epidemiologist John Newton for the position of CEO. Newton has been the consultant epidemiologist at the Department of Public Health and Primary Care at Oxford for eleven years, and was also director of R&D at the Oxford Radcliffe Hospitals NHS Trust.

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The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.