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The Bottom Line: Feb 9, 2001

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A number of companies have reported their earnings for the quarter ending December 31, 2000, over the last few weeks. BioInform has tabulated the quarterly earnings for some leading bioinformatics companies below. All figures are in millions of US dollars. For a more complete breakdown of the companies’ earnings reports, please see GenomeWeb’s coverage at www.genomeweb.com.

*For comparative purposes, Lion’s earnings were converted from euros to US dollars based on the conversion rate as of February 8, 2001. Please see www.genomeweb.com for Lion’s reported earnings in euros.

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The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.