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BioWisdom, Amgen, InforSense, Crosslinks, Van Andel Research Institute, Definiens

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Amgen to Use BioWisdom's Sofia Software
 
Amgen has signed a multi-year license agreement to use BioWisdom’s knowledge network software, BioWisdom said this week.
 
BioWisdom’s Sofia software is used to format large amounts of complex data that drug developers generate in their research. The Cambridge, UK-based firm said the software creates “Intelligence Networks,” which it defines as “a unique format of assertional metadata that liberates knowledge from structured and unstructured data, regardless of its original format.”
 
Financial terms of the agreement were not released.
 

 
Crosslinks Joins InforSense Partner Network
 
InforSense said this week that Dutch bioinformatics services firm Crosslinks has joined the InforSense Open Partner Network as a certified provider of its workflow technology.
 
Crosslinks is a spinoff from the Erasmus MC Department of Bioinformatics and provides analysis of genomics and proteomics data.
 
Through the alliance, Crosslinks becomes a preferred InforSense Services Provider in Europe for both academic and commercial customers. It also operates a demonstration center in the Netherlands for InforSense’s technology.
 
The InforSense platform will allow Crosslinks to fulfill “growing demand for large-scale, genome-wide analyses,” Crosslinks CEO Ronald Nanninga said in a statement. He said the firm would apply the technology to bioinformatics data analysis in research and diagnostic applications.
 

 
Children’s Memorial Research Center Licenses Van Andel’s XenoBase
 
The Van Andel Research Institute said this week that Chicago’s Children's Memorial Research Center has licensed its XenoBase software and database system under a multi-year agreement.
 
XenoBase was designed to collect and analyze molecular and clinical data to help researchers identify associations between diseases, biomarkers, and treatment outcomes. The institute said that physicians have used the platform “to match the molecular profile of tumors of late-stage cancer patients to the most effective therapy, based on molecular evidence.”
 
CMRC will use XenoBase to study the molecular and clinical basis for disease and to discover new therapeutics.
 
Financial terms of the agreement were not disclosed.
 

 
Montpellier Rio Imaging to Use Definiens' Image Analysis Software
 
Montpellier Rio Imaging will use Definiens’ high-content image analysis and data management technology at its lab in the Languedoc-Roussillon region of France, Definiens said this week.
 
MRI said it will use the technology in its automated offerings for cell-based assays and large-scale histopathology research.
 
Financial terms of the agreement were not released.

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The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.