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Biosis,TheScientificWorld,Weizmann Institute, Genops Bioinformatics

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Biosis, a Philadelphia-based non-profit organization that accumulates and organizes abstracts and bibliographic references to biomedical literature, has collaborated with TheScientificWorld of Boynton Beach, Fla., to launch methodsBase, a research tool available through www.thescientificworld.com. The tool features links to full-text journal articles, patents, and services for procuring laboratory and biological resources.

Updated weekly, methodsBase currently performs free-text searches on more than 175,000 classified and indexed records selected from scientific journals, books, conference proceedings, patents, protocols, and websites.

 

Israel’s Weizmann Institute has made version 2.23 of the GeneCards database of human genes available at http://bioinformatics.weizmann.ac.il/cards.

The latest release includes 27,612 genes and 51 gene clusters, an expanded SNPs section, and gene description information for C. elegans homologs.

 

Genops Bioinformatics has ported its sequence analysis platform, Ngene, to Mac OS X and has added an evaluation version to the Windows-based trial already available from www.genops.com/down- load/default.htm.

 

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The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.