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biOpen, Ensembl 22, Tata Bio-Suite, GCOS SDK, RNA integrity number, EMBL Nucleotide Sequence Database, Control Tower 6G

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AbOrygen has released biOpen, a DNA and protein sequence analysis and 3D structure visualization software package, for Mac OS X. A demo is available at http://www.aborygen.com/downloads/biOpen/.


Ensembl 22 is available at www.ensembl.org. The release contains MultiContigView, a comparative genomics display for viewing two or more genomes, and also includes the first annotated draft chicken (Gallus gallus) assembly, with 17,784 genes with 185,326 exons.


Tata Consultancy Services has launched a beta version of Tata Bio-Suite, a set of eight bioinformatics modules for sequence analysis, genome analysis, comparative genomics, 3D modeling, 3D structure manipulation, structural analysis, simulation, and drug design.


Affymetrix has released version 1.2 of the GeneChip Operating Software Developer’s Kit (GCOS SDK) at http://www.affymetrix.com/support/developer/gcos_sdk/gcos_sdk_download.affx. The update includes a pre-release copy of the GCOS 1.2 software. The company has also released Files SDK 4.0, which supports the new file formats generated by GCOS 1.2.


Agilent Technologies has released new software to assess RNA quality and grade it on a quantitative scale of 1 to 10 — a measurement it calls the RNA integrity number (RIN). The software works with the company’s 2100 Bioanalyzer and RNA Nano LabChip kits. Bioanalyzer customers can download a free beta version at www.agilent.com/chem/RIN.


Release 79 of the EMBL Nucleotide Sequence Database is available from ftp://ftp.ebi.ac.uk/pub/databases/embl/release/ (UK) and mirror sites. Release 79 is about 30 GB compressed and 187 GB uncompressed.


RLX Technologies said it will release a new version of server management software, called Control Tower 6G, in July. The software includes an Automation Policy Manager feature that uses rules-based policies to implement actions in response to alerts or infrastructure monitoring.

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The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.