BioInform s Patent Roundup: Recent Patents of Interest in Bioinformatics

May 05, 2003

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Patent 6,554,987. Method and apparatus for alignment of signals for use in DNA base calling. Inventors: Rodney Gilchrist, Vrijmoed Chi. Assignee: Visible Genetics.

Protects a method of aligning data traces from a four-channel automated electrophoresis detection apparatus. An optimization routine such as a simulated annealing algorithm is used to determine coefficients of stretch and shift in order to normalize and align the data traces.

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