Phenotype Microarrays for Drug Toxicity Screening. Start date: May 2003. Expires: April 2004. Principal investigator: Barry Bochner. Institution: Biolog. NIH Institute: NCI.
Project to use Biolog’s Phenotype Microarrays to build a prototype database of metabolic profiles for well-studied drugs in human liver and hematopoietic cell lines that can be used to screen small molecules for toxicity potential. The project will eventually lead to a predictive database that will include cell lines representing more tissues and organs.