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BioInform s Funding Update: Some Recent NIH Awards in Bioinformatics: Mar 10, 2003

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Interdisciplinary Center for Structural Informatics. Start date: Jan. 2003. Expires: Nov. 2005. Amount: $613,444. Principal Investigator: James Brinkley. Institution: University of Washington. NIH Institute: NLM.

Proposal to create an information framework called the Interdisciplinary Center for Structural Informatics that would link diverse types of biomedical data and knowledge in a large-scale distributed information system.

 

Development of Bioinformatic Tools for Virtual Cloning. Start date: Feb. 2003. Expires: Aug. 2003. Amount: $100,000. Principal investigator: Jeremy Bruenn. Institution: Virmatics. NIH Institute: NIGMS.

Project aims to develop a task-centered virtual cloning expert system that serves as a knowledge base for DNA manipulations, and also to develop an “information automaton” for the construction of expression clone libraries to support structural genomics initiatives and other high-throughput experiments.

 

A Novel Pattern-Based Framework for Genetic Analysis. Start date: March 2003. Expires: February 2004. Principal investigator: Zhong Li. Institution: First Genetic Trust. NIH Institute: NCI.

Project will develop a data analysis method to map complex traits that consider all possible genetic mechanisms using a pattern discovery-based approach and a collection of theoretically and empirically derived statistics to identify multi-locus disease associations.

 

Proteomics Software Package for the Detection of Cancer. Start date: April 2003. Expires: Sept. 2003. Principal investigator: Maciek Sasinowski. Institution: Incogen. NIH Institute: NCI.

Phase I SBIR project to develop a software package to diagnose cancer based on classification of proteomics data obtained through mass spectrometry, particularly MALDI/SELDI TOF mass spec data. Initial work will focus on exploring the applicability of various existing statistical approaches for signal conditioning and classification of SELDI proteomics data.

 

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