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Benchware, mpiBlast, EBIMed, GenePart, Flu Sequence Dataset Explorer, Splign, gMap, STN AnaVist, Neil Dey, Rudolph Potenzone, Steven Enoch


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Tripos said that it will launch its Benchware laboratory informatics suite at the Drug Discovery Technology conference in Boston, Aug. 9-11. The Benchware portfolio includes: Benchware 3D Explorer, a chemical visualization and decision-support tool; Benchware HTS DataMiner, a lead series prioritization tool that was formerly marketed by Tripos under the product name SARNavigator; Benchware LibraryMaker for enumerating parallel compound libraries; and Benchware LibraryDesigner for helping chemists decide which reactants to use when making parallel compound libraries.

Version 1.4.0 of mpiBlast is available at The release includes a number of enhancements in performance, scalability, and stability, according to its development team, and attained a 305-fold speedup over NCBI Blast with 128 CPUs. The previous mpiBlast release provided only 180-fold speedup on the same data set.

EBIMed, a document retrieval and extraction tool, is available from the European Bioinformatics Institute at The extracted information provides an overview on associations between UniProt proteins, GO annotations, drug names, and species, as well as links to the relevant sentences, the original abstracts, and the biological databases that contain them.

Informed Bioscience of Bozeman, Mont., has released a beta version of its GenePart microarray-analysis software. The company claims that the software is able to "almost perfectly" discriminate tissue classes based on microarray data.

The National Center for Biotechnology Information has released the Flu Sequence Dataset Explorer, an interactive tool for performing preliminary analysis on protein and nucleotide sequences from the NCBI Influenza Sequence Database, at NCBI has also released Splign (Spliced Alignment), a new utility for computing cDNA-to-genomic alignments or spliced sequence alignments, using Blast, at Additionally, the institute released gMap, a microbial genome comparison tool, at

Chemical Abstracts Service and FIZ Karlsruhe have launched STN AnaVist, a patent-analysis software tool. Features include content from multiple sources, including CAplus, PCT, and the US full-text patent databases; relationships between structured and unstructured data; data grouping and cleanup; concept standardization; and flexible creation of result sets. The software is available through Dec. 31 at no charge at


People in the News

Definiens has appointed Neil Dey as vice president of business development and marketing. The company said in a statement that Dey's appointment is "the first of multiple planned moves to prepare the company for significant growth in the Americas and Europe throughout 2005 and 2006." Dey joins the firm from BioImagene, where he served as vice president of business development. He was also head of business development at Impath, and has held senior executive positions at Genmethrax, Thomas Jefferson Medical University, and Ciba-Geigy (Novartis).

Rudolph Potenzone has joined CambridgeSoft as vice president of enterprise solutions. Potenzone most recently served at Ingenuity, which he joined last March as senior vice president of business development and strategic planning. Potenzone was previously CEO of Lion Bioscience's US subsidiary, Lion Bioscience Inc. He also worked at MDL as senior vice president for marketing and development, and held positions at Chemical Abstracts Service and Polygen/Molecular Simulations.

Peakdale Molecular has appointed Steven Enoch to head its computational chemistry department. Enoch joins the firm from Cyprotex Discovery, where he served as a chemoinformatician.

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The Scan

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Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.