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BD Biosciences Clontech, Lynx Therapeutics, European Bioinformatics Institute, LifeSpan BioSciences, MiraiBio


The bioinformatics department of BD Biosciences Clontech of Palo Alto, Calif., has released the BioCalculator bioinformatics toolkit through its BioInfo website ( The freely available tool is designed to work with gene sequences in batch mode and includes gene list validation as well as addition and subtraction tools performed by matching sequences against UniGene, LocusLink, and GenBank databases.

Hayward, Calif.-based Lynx Therapeutics has released its Massively Parallel Signature Sequencing data through the Celera Discovery System. The MPSS databases contain gene expression data derived from normal human tissues analyzed using Lynx''''s MPSS technology. Signature sequences from the MPSS data are mapped to the Celera human genome assembly.

Release 20.0 of the Trembl protein sequence database is now available from the European Bioinformatics Institute at or Trembl 20.0 contains the translations of all coding sequences in release 69 of the EMBL Nucleotide Sequence Database not yet integrated in SwissProt. It contains 700,753 entries and 203,489,769 amino acids.

LifeSpan BioSciences of Seattle has launched a new subscription database called DrugTarget, which combines proprietary immunohistochemistry data with manually curated data covering more than 2,000 human genes from eight gene families.

The relational database includes thousands of digital photomicrographs of immunostained tissue specimens from the company’s bank of tissue specimens. Curated public data includes information on protein and nucleic acid sequences, expressed sequence tags, clones, publications, and patents.

Subscriptions to DrugTarget are available for a yearly fee, with a minimum three-year commitment.

MiraiBio, an Alameda, Calif.-based subsidiary of Hitachi Software Engineering, has released version 3.0 of its Image Analysis software for viewing and analyzing scanned images of gels, membrane, microarray slides or microtiter plates. New features in version 3.0 include automatic lane detection and lane lifting, lane bending, image file export, image comparison, batch analysis support, and more, according to the company.

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The Scan

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Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

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Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

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Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.