Bayer s Alexander Hillisch on the Pros and Cons of Homology Modeling | GenomeWeb

In silico drug design shows promise as a quick, low-cost alternative to high-throughput screening and other expensive experimental methods, but the field has been hampered by the limited number of three-dimensional protein structures that have been experimentally derived. As quickly as the Protein Data Bank is growing (PDB contained 29,101 structures as of Jan.

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