NEW YORK (GenomeWeb) – Researchers from the University of California, San Francisco and the Gladstone Institutes have developed a new integrated computational pipeline — the Metagenomic Intra-Species Diversity Analysis System (MIDAS) — to quantify bacterial species abundance and strain-level genomic variation, including gene content and SNPs, from shotgun metagenomes.

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With the Next Generation Sequencing (NGS), genomes sequencing has been democratized over the last decades with the detection of genomic alterations, thus replacing Sanger sequencing.