Back to Basics: TIGR Meeting Highlights Need for Improved Annotation, Assembly Methods | GenomeWeb

RESTON, VA. —Everything old was new again at this year’s TIGR/Jackson Laboratory Computational Genomics conference, held here Oct. 21-24, where talks focused on genome assembly, annotation, gene prediction, and other old-school bioinformatics methods.

Coinciding with the publication on Oct. 22 of the “final” version of the human genome, which pegged the upper end of the human gene count at a seemingly low 25,000, the meeting underscored just how far first-generation bioinformatics methods like ab initio gene prediction still have to go.

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