Skip to main content
Premium Trial:

Request an Annual Quote

Athena, CombiChem Partner to Discover Drugs To Treat CNS Conditions


SAN DIEGO, Calif.--The computational drug discovery company CombiChem here will collaborate with Athena Neurosciences to discover drugs to treat central nervous system conditions. Athena, a wholly owned subsidiary of the international biopharmaceutical company Elan, also made an equity investment in CombiChem.

The agreement gives CombiChem up-front, research support, and milestone payments. Athena will have exclusive worldwide rights to develop and market any products that result from the collaboration, and CombiChem will receive royalties on product sales.

In the collaboration, CombiChem will utilize its proprietary Discovery Engine technology to generate lead candidates. Athena has the right to use CombiChem's Universal Informer Library of compounds.

"This is a very significant collaboration for CombiChem and represents an excellent opportunity to apply our technology to multiple targets in yet another therapeutic area," commented Vicente Anido, CombiChem's president and CEO. Ivan Lieberburg, Athena's vice-president of research, added, "We believe CombiChem's advanced technology in small molecule drug discovery, coupled with Athena's proprietary assay systems, represent a truly exciting collaboration in our quest to identify treatments for Alzheimer's and other CNS diseases."

In other news, CombiChem announced this month that it has registered with the US Securities and Exchange Commission for an initial public offering of 2.25 million shares of common stock, at an estimated price of $11-$13 per share. BancAmerica Robertson Stephens is the lead managing underwriter for the offering, with Donaldson, Lufkin & Jenrette Securities and UBC Securities acting as comanagers.

Filed under

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.