To Assess Genome Assemblers, Steven Salzberg Organizes a Bake-Off | GenomeWeb

As sequencing technologies change, a whole host of software — genome assembly software, to name one category — has to change with them. To assemble a genome correctly, researchers have to have the right software, and the choice of which program to use often depends on the genome itself, as well as which technology was used to sequence it. "Sometimes the assembler that's the best for one genome isn't the best for another genome," says the University of Maryland's Steven Salzberg.

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