As sequencing technologies change, a whole host of software — genome assembly software, to name one category — has to change with them. To assemble a genome correctly, researchers have to have the right software, and the choice of which program to use often depends on the genome itself, as well as which technology was used to sequence it. "Sometimes the assembler that's the best for one genome isn't the best for another genome," says the University of Maryland's Steven Salzberg.

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360Dx reports that the US Centers for Medicare & Medicaid Services would cover next-generation sequencing-based cancer panel tests.

The Washington Post reports that a meteorologist is being considered as presidential science and technology advisor.

In PNAS this week: precision medicine strategy to screen for disease risk, genome evolution in Haemophilus influenzae, and more.

Researchers have developed a PCR-based assay to gauge whether manatees are present in waters.