The results of the second Assemblathon challenge, hosted by researchers at the University of California, Santa Cruz and UC Davis, indicate that although current de novo genome assembly software can produce useful assemblies there is still a lot of room for improvement.

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In PLOS this week: new gene linked to ocular coloboma, new statistical model for interrogating gene expression networks, and more.

With a new collection, PLOS highlights negative results it has published.

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