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ApoCom Genomics, Nonlinear Dynamics, TurboGenomics, Pfam, Accelrys

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ApoCom Genomics of Knoxville, Tenn., has released GrailEXP, an enhanced version of the Grail genome sequence analysis software package. GrailEXP includes experimental and evidence-based data such as ESTs, mRNAs, cDNAs and other gene messages in the modeling process to strengthen predictions, according to ApoCom. The company is currently offering a 20 percent license discount to commercial users of GrailEXP.

Nonlinear Dynamics, based in Newcastle upon Tyne, UK, has launched Phoretix Evolution, 2D gel analysis software positioned between the company’s low-throughput Phoretix 2D and high-throughput Progenesis products. According to Nonlinear, Phoretix Evolution utilizes some technology from the Progenesis range for advanced functionality. In addition, Nonlinear has expanded the Progenesis range with two new products: Progenesis Workstation for medium to high throughput, and Progenesis Discovery, a solution for automated high-throughput gel analysis that will be launched later this year.

TurboGenomics of New Haven, Conn., has released TurboBench 2.0, a software platform that enables distributed computing with heterogeneous mixtures of multiprocessor servers, clusters, networked desktops, and computational grids without rewriting their current applications. The Java-based infrastructure of TurboBench 2.0 is compatible with all major hardware platforms and operating systems, including Linux, Unix, Windows, and Mac OS X.

Version 7.5 of the Pfam collection of protein domain family alignments constructed using profile hidden Markov models is available from the Pfam consortium at: www.sanger.ac.uk/Software/Pfam, pfam.wustl.edu, and www.cgr.ki.se/Pfam. Pfam 7.5 contains 4,176 families.

Accelrys said its Accord Enterprise Informatics suite, the latest in its Discovery Studio line of software offerings, would be available in mid-September. The Accord suite stores and manages corporate chemical, biological screening, and inventory data.

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The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.