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Alma Bioinformatica, Applera, Genetic-Xchange, Wellcome Trust Sanger Institute


Alma Bioinformatica of Madrid, Spain, has released JSOTA, a Java-based implementation of the company’s proprietary Self-Organizing Tree Algorithm (SOTA) for expression data analysis.

SOTA is a neural network that grows adopting the topology of a binary tree. The software is available at


Applera’s Applied Biosystems Group, based in Foster City, Calif., has released its Pro ICAT software for the API QSTAR Pulsar Hybrid LC/MS/MS system. According to ABI, the new software automatically identifies and quantifies proteins when used to analyze tandem MS data from ICAT reagent-based proteomics experiments.


Menlo Park, Calif.-based Genetic-Xchange has released the “Oracle Edition” of its K1 Data Integration Middleware Platform. The new edition gives Oracle users a direct connection to over 50 life science data sources and algorithms from within the Oracle environment, according to the company.


Release 7.0 of the Pfam collection of protein domain family alignments is now available from the Wellcome Trust Sanger Institute at

The release contains 3,360 families. Since Pfam 6.0, 320 new families were added and 33 families were deleted.

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The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.