What are the biggest scientific hurdles that the pharmaceutical industry is looking to solve with informatics? The short list may surprise you.

According to attendees of the inaugural meeting of Accelrys’ newly launched science council — which includes representatives from a baker’s dozen of the software company’s largest pharma customers — five topics stand out as the prize problems: ADME/tox prediction; ligand/protein docking; integrating clinical data into discovery research; workflow automation; and software-enabled medicinal chemistry.

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Two researchers have found that behavioral genetic defenses in criminal cases don't tend to affect outcomes, according to Popular Science.

Researchers report that while host genetics influence the oral microbiome, they don't appear to affect cavity-causing microbes, the Economist says.

Pandas' gut microbiomes change as what they eat changes with the seasons, writes Discover's Inkfish blog.

In PLOS this week: comparative genomic study of malaria-linked macaque parasite, search for apple root reference genes, and more.