NEW YORK (GenomeWeb) – Scientists from the University of Massachusetts Medical School have engineered a new way to do CRISPR/Cas9 genome editing by fusing a mutant Cas9 with earlier technologies used in the field, such as zinc finger proteins.

Led by senior author Scot Wolfe and first authors Mehmet Bolukbasi and Ankit Gupta, the researchers published their proof-of-concept study last week in Nature Methods.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

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About one year ago, the Association for Molecular Pathology (AMP), with liaison representation from the American College of Medical Genetics and Genomics (ACMG), American Society of Clinical Oncology (ASCO), and College of American Pathologists (CAP), released a guideline on reporting somatic cancer variants.