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IsoPlexis, Institute for Systems Biology Partner to Identify COVID-19 Immune Mechanisms

NEW YORK – IsoPlexis has partnered with the Institute for Systems Biology (ISB) to map functional immune response to COVID-19 at the single-cell level.

The group will use IsoPlexis' single-cell functional platform to analyze immune cells from individuals who have been diagnosed or recovered from COVID-19. The team aims to examine a variety of immune cell types — including various T cells and myeloid cells — to put together a map of the overall response.

"Critical information from all aspects of the immune response will be key in understanding how to fight [COVID-19] and address complications," James Health, president of the ISB, said in a statement. "Functional phenotypes of each immune cell, using IsoPlexis' system, will be a cornerstone of the understanding of this immune response in affected patients."  

Financial details of the collaboration were not disclosed.

"Through our unique functional analysis of each cell, we can unlock further understanding of how COVID-19 interacts with the immune system," Sean Mackay, CEO and cofounder of IsoPlexis, said in a statement. "Cellular immune signatures based on cytokines may be key in understanding and predicting response, and also how to mitigate disease progression."