NEW YORK – A CRISPR-based loss-of-function screen has identified host genes that are needed for SARS-CoV-2 to infect human lung cells, pointing to potential novel treatment targets for COVID-19.
SARS-CoV-2 has infected more than 40 million people worldwide, leading to more than 1 million deaths. While a number of vaccines against SARS-CoV-2 are in clinical trials, others are looking for potential therapeutics to treat COVID-19.