Hybrigenics Presents Data on Investigational Anti-Cancer Agent That May Need Companion Test | GenomeWeb

By Turna Ray

HX 41,108, an anti-cancer agent being developed by Hybrigenics, has demonstrated in preliminary studies that it can inhibit ubiquitin-specific protease no. 7, an enzyme critical to the regulation of the tumor suppressor protein p53.

The data, while preliminary, suggests that the drug might require a companion diagnostic to establish p53 status prior to treatment, company officials said.

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