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How Handy?

In the Pipeline's Derek Lowe wants to know, of what value is a scientific background in jobs not relating to research, or in life in general? The "ideas of a scientist's world view," he says, are pretty "basic." First, the natural world goes on no matter what humans think or believe at any given moment. Next, the natural world conforms to a set of rules — these could be complex, but they can be figured out. Third, Lowe says, the way to figure out these rules is to "ask questions of the world in an organized fashion" through observations or experiments. And finally, he adds, since the world is so complex, it's better to ask questions that are as well thought-out as possible. A scientific outlook is the backdrop for the entire modern world, Lowe says, and therefore must be worth something. "I think that for any kind of work that requires brainpower and adaptability, a scientific background should come in handy," he adds. The real question is, "how handy?"

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.